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Fully-automatic for example, without human intervention or semi-automatic operation for example, computer processing assisted by human intervention can be supported.

User intervention may be desired in some cases, such as to adjust parameters or consider results. Such software can be stored on one or more computer-readable media comprising computer-executable instructions for performing the described actions.

The techniques described above classify and explain an individual's level of familial risk for one or more diseases of interest.

One embodiment is a method for determining the extent to which personal and family health histories play a role in developing a disease of interest in a subject, the method comprising: obtaining the subject's personal and family health histories including one of the group consisting of history of the disease of interest, history of indicator diseases, and history of indicator traits; and referencing a familial disease risk matrix using the subject's obtained personal and family health histories to find the subject's assigned level of familial risk of the disease of interest.

Through identification of all intersections that arise for any given subject for any given disease of interest, a determination can be made regarding the highest level of familial risk for a disease of interest.

In such an embodiment, each intersection of medical history characteristics may further give an explanation for the given level of familial risk by citing the relevant personal and family history characteristics, including the possibility that these characteristics are suggestive of an inherited form of a disease.

In yet another embodiment, a machine-readable medium contains instructions stored therein which, when executed by a machine, implement an algorithm that determines the highest level of familial risk for a disease of interest for a subject.

Each intersection may further give an explanation for the given level of familial risk by citing the relevant personal and family history characteristics, including the possibility that these characteristics are suggestive of an inherited form of a disease, and when two or more intersections of medical history characteristics of the same level of familial risk are identified, all of the relevant explanations identified for each intersection of medical characteristics may be provided without redundancy or inconsistency according to an algorithm that considers all possible explanations of familial risk of a disease of interest.

It should be also be noted that the familial risk matrices, algorithms, or tables described above may be combined with other risk assessment techniques that consider other risk factors for disease, to give a more complete individualized risk assessment.

Examples of such risk factor categories used by other risk assessment techniques include demographic factors e. As such, a personal and family history risk table or matrix may become part of a disease risk assessment tool that in effect has multiple dimensions.

Having illustrated and described the principles of the invention in example embodiments, it should be apparent to those skilled in the art that the described examples are illustrative embodiments and can be modified in arrangement and detail without departing from such principles.

Techniques from any of the examples can be incorporated into one or more of any of the other examples. In view of the many possible embodiments to which the principles of the invention may be applied, it should be understood that the illustrative embodiments are intended to teach these principles and are not intended to be a limitation on the scope of the invention.

For example, the functionality of a matrix, array, or look-up table may be implemented in a computer program using only if-then statements or using an expert system.

I therefore claim as my invention all that comes within the scope and spirit of the following claims and their equivalents. All rights reserved. Login Sign up.

Search Expert Search Quick Search. Method and apparatus for determining familial risk of disease. United States Patent Personal and family health history information can be used to assess familial risk of disease.

For example, information can be collected about the disease history of a person and the person's first- and second-degree relatives and then analyzed to determine the familial risk of common diseases such as coronary heart disease, stroke, type 2 diabetes, and colorectal, breast, and ovarian cancer.

Assessed familial risk of disease can then be used by researchers to better estimate the contribution of personal history and family history to the etiology and natural history of a disease of interest, and by consumers and health professionals to determine recommendations for disease management, prevention and screening that are personalized and targeted to the familial risk.

Other embodiments are also described and claimed. Scheuner, Maren Theresa Manhattan Beach, CA, US. Click for automatic bibliography generation.

Download PDF Maren T. Scheuner, et al. Jon Emery, et al. PCT International Search Report dated Aug. Acheson, Louise S.

Acheson, MS, MD, Louise S. Coulson, A. Emery, Jon, et al. Emery, J. Hampel, H. Hariri, PhD, Susan, et al. Henderson, MD, L.

Qureshi, M. Scheuner, Maren T. Scheuner, MD, MPH, Maren, et al. Simon, PhD, Christian, et al. Sweet, Kevin M. Westman, Judith, et al. I learned from them a lot, much more than reading books.

In truth, I learned what is never told. Here is their music - the sound of Midtown - Bang! Records wants to share with you!

In an experimental lab, Dr. Brighton created AWO with early versions of his molecular digitizer. Four Memphis musicians, at crossroads in their musical careers submitted themselves as subjects for Dr.

He sent them through the molecular machine and they joined forces as AWO on the other side. Veteran musicians of Memphis and New Orleans, the members came from established bands such as Neighborhood Texture Jam, Compulsive Gamblers, Royal Pendletons, Doctor-A-Go-Go and The Wallendas.

Slipping into a riff-rock groove and pounding it became the style of the band. However, the initial success of the band was short lived as Parkinson became victim to the side effects of molecular digitization and left Memphis in search of Dr.

AWO enlisted the help of veteran drummer Chris Craig of Black Oak Arkansas and Lord Tracy. This lo-fi rock anthem captures the spirit and feel of an old rock show at an auditorium full of sex dolls.

His spaceship crash landed deep in the heart of Memphis after a few cosmic collisions with New York and Nashville. Backed by local misfits and sometime-legends, he has become know for his all-night, bar-dancing, guitar-levitating, brown-liquor-down-the-back-of-your-throat live shows.

The indie band Kindza from Kolomna Moscow region, Russia has released a short animated movie to the title melody of their new album Common Friends. This cartoon….

From Paul Felton - Branding, Illustration, Layout Inspirational and colourful editorials for Kate Beavis Your Vintage Life, vintage blogger, writer and speaker on homes, fashion, weddings and lifestyle.

With scientific advances, Medicaid expansion, and political consensus on the importance of improving mental health, the time is ripe for transforming the U.

This will mean structural reforms that address patients' challenges in finding, accessing, and receiving high-quality and timely care.

Any device can be hacked, including one inside the human body. We need to think through the privacy and security implications of devices that live with us.

But we should also consider the life-changing, life-saving potential of technologies that know us inside and out. Telehealth use skyrocketed during the COVID pandemic.

Can this form of high quality, low cost care be maintained post—COVID? Shih, M. Professor of Neurosciences at UC San Diego Director of the Center for Neural Repair.

Gage, M. Brumback, M. Kordower, PhD The Jean-Schweepe-Armour Professor of Neurological Sciences an Director Research Center for Brain Repair Prevention of Stroke: Taking Advantage of Some Newer and Not so Newer Technologies Ashfaq Shuaib, MD, FRCPC Professor of Medicine and Neurology Director, Stroke Program University of Alberta, Canada Stroke Research: History and Future John H.

Louis Facing the Daunting Tasks Post Recent Endovascular Stroke Trials: Treating More Patients and New Therapy Osama Zaidat, MD, Professor and Director Comprehensive Stroke Program, Medical College of Wisconsin Three Topics in Neuro-Oncology David Piccioni, MD, PhD, Assistant Professor of Neuroscience and Neuro-Oncology, UC San Diego Developmental Dyslexia: Genes, Brains, Behaviors Albert Galaburda, MD, Professor of Neurology Co-Director, Mind Brain Behavior Initiative, Harvard University An Update on Biomarkers for Parkinson's Disease Peter LeWitt, MD, Professor of Neurology Wayne State University Director, Parkinson's Disease and Movement Disorders Program, Henry Ford West Bloomfield Hospital, Michigan Brain Computer Interface Based Stroke Rehabilitation Vivek Prabhakaran, MD, PhD Assistant Professor of Radiology Dept.

Fulton ALS and Neuromuscular Disease Center, Barrow Neurological Institute. Inflammatory Myopathies: Translational Studies Steven A. Greenberg, MD Associate Neurologist, Brigham and Women's Hospital Associate Professor of Neurology, Harvard Medical School Primary Progressive Apraxia of Speech: Clinical, Neuroimaging and Molecular Features Keith A.

Josephs Jr. Tong MD, FAHA, FAAN FANA Medical Director California Pacific Medical Center CPMC Comprehensive Stroke Center CCSC Director Clinical Professor of Neurology, Geisel School of Medicine at Dartmouth, CPMC Center for Stroke Research, San Francisco Advances in EEG-Based Neurodynamics Jeffrey Gertsch, MD Medical Director, Surgical Neurophysiology UC San Diego Dept.

Can we face the challenge? Tanya Simuni, MD Professor of Neurology; Director, Parkinson's disease and Movement Disorders Center Northwestern University Feinberg School of Medicine CSF: Insights into MS Patricia Coyle, MD Professor, Neurology; Director, MS Comprehensive Care Center Stony Brook University Medical Center Neurogenetics: a medical geneticist's view from the trenches Maren T.

Scheuner, M. Lewis, MD Director, EMG Neurology and Special Clinics Cedars-Sinai Medical Center, Los Angeles. Pellock, MD Professor and Chair, Child Neurology Senior Associate Dean for Professional Education and President and CEO, UHS Professional Education Programs, Inc.

The company is listed on the New York Stock Exchange and is controlled by the Ford family; they have minority ownership but the majority of the voting power.

Archduke Franz Ferdinand, Archduke of Austria-Este was a member of the imperial Habsburg dynasty, and from until his death the heir presumptive Thronfolger to the Austro-Hungarian throne.

Martha Hartwig Scheuner was 35 years old when The Nineteenth Amendment to the United States Constitution was ratified, guaranteeing women's suffrage in America.

The Nineteenth Amendment to the United States Constitution prohibits the states and the federal government from denying the right to vote to citizens of the United States on the basis of sex.

It was adopted on August 18, Martha Hartwig Scheuner was 54 years old when World War II: Nazi Germany and Slovakia invade Poland, beginning the European phase of World War II.

The vast majority of the world's countries—including all of the great powers—eventually formed two opposing military alliances: the Allies and the Axis.

It was the most global war in history; it directly involved more than million people from over 30 countries.

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